digestive problems – The Nutrition Supplement Dietitian

Gut-Brain Reset – Probiotic for Mood + Digestive Comfort, IBS

ALS — Thu, 08 Jan 2026 20:49:43 +0000

Gut-Brain Reset – Dual Action Probiotic Combo Supporting Digestive Comfort and Mood Self-Regulation

Psychobiotic/Probiotic Combination
Formerly called ZenBiome DUAL

Revolutionary Way to Support Healthy Gut-Brain Axis with Two Clinically Studied Unique Strains:

Bifidobacterium longum — 1714 a Psychobiotic for Mood
Bifidobacterium longum 35624 for Functional GI Disorders Like IBS

Gut-Brain Reset is a revolutionary dual-action probiotic combination is designed to address both functional GI disorders such as IBS and psychosocial comorbidities such as depression and anxiety.

Recent research has established a shared etiology for both disorders: a dysfunction in the gut-brain axis.

Powered by the innovative combination of Bifidobacterium longum 1714 and Bifidobacterium longum 35624, this unique formula targets the gut-brain axis, offering clinically demonstrated relief for IBS symptoms and associated psychological stress.

Bifidobacterium longum 1714 is a trailblazing psychobiotic strain that supports cognitive function, mood regulation, sleep quality, and stress response and its biochemical expression within the body. This psychobiotic exerts its effect by targeting the HPA axis to support healthy cortisol levels.

Bifidobacterium longum 35624 has 85 published studies showing efficacy in IBS symptoms, including a reduction in IBS Severity Symptom Scores across the board. This strain adheres to intestinal epithelial cells and the gut barrier’s mucous layer, supporting a calming effect and helping to maintain relief from abdominal discomfort, gas, bloating, constipation, and/or diarrhea. Supportive in all types of IBS — IBS-C, IBS-D and IBS-M.

The Gut-Brain Axis and Functional GI Disorders

The gut-brain axis is a bidirectional communication pathway between the gut microbiota and the central nervous system (via the vagus nerve). The signaling along this pathway is important for healthy digestion, GI comfort, cognitive function and mood.

When gut-brain axis is disturbed, the gut and brain no longer work together seamlessly. The digestive tract can become sensitive. Bowel muscle contractions may be altered. The GI system doesn’t function properly, hence the term Functional GI disorders. IBS is one example of a Functional GI disorder.

Symptoms of Functional GI disorders may include abdominal discomfort, gas, bloating, constipation, diarrhea or a combination of alternating constipation and diarrhea.

IBS, Psychosocial Disorders, Gut-Brain Axis Conditions

IBS has been linked to a dysfunctional microbiome, an altered immune response in the gut, sensitive to stress and comorbid anxiety and depression in the brain.

Gut dysbiosis disrupts tryptophan metabolism which can result in byproducts that are neuroinflammatory, contributing to mood disorders.

Clinical Research: Bifidobacterium longum strains 1714® and 35642® Combination

A recently published study explores the impact of the probiotic combination in Gut-Brain Reset: Bifidobacterium longum strains 1714® and 35642®

Interactions between symptoms and psychological status in irritable bowel syndrome: An exploratory study of the impact of a probiotic combination – Groeger – 2023 – Neurogastroenterology & Motility – Wiley Online Library

40 females (18-65y) with IBS & mild to moderate anxiety and/or depression supplemented with the probiotic combination (1 × 109 cfu/day) for 8 weeks. Outcome measures included: IBS Symptom severity (abdominal pain, abdominal pain frequency, abdominal distension severity, bowel habit satisfaction, quality of life), anxiety scores, depression scores, sleep quality, cortisol output and inflammatory biomarkers were taken weeks 0-16.

Key Findings:

82% of patients experienced a clinically significant improvement in IBS symptom severity
Significant improvements were seen in depression scores, anxiety scores, sleep quality, and quality of life
Normalization of the cortisol response was observed
Improvements in inflammatory biomarkers (TNF-a, IL-6, and CRP) were correlated with beneficial effects on anxiety and depression

The Gut-Brain Axis and the Psychobiome

The gut-brain axis, a bidirectional communication between gut microbiota and the central nervous system (CNS), may play a role in cognitive function, digestion, and mood.

Studies show that 80-90% of the fibers in the vagus nerve are linked to the gut, providing a physical link through which the gut microbiota communicate with the brain.

Relatedly, the term psychobiome is used to describe the interaction between a person’s collective microbiome and their mental state.

A diverse and balanced microbiome can help maintain the gut-brain axis. A psychobiotic is used to describe the commensal bacteria that play a role in the gut-brain axis and support brain health.

About Psychobiotics and the Gut-Brain-Microbiota Axis

“The gut-brain-microbiota axis consists of a bilateral communication system that enables gut microbes to interact with the brain, and the latter with the gut. Gut bacteria influence behavior, and both depression and anxiety symptoms are directly associated with alterations in the microbiota.”

“The action mechanisms by which bacteria exert their psychobiotic potential has not been completely elucidated. However, it has been found that these bacteria provide their benefits mostly through the hypothalamic-pituitary-adrenal (HPA) axis, the immune response and inflammation, and through the production of neurohormones and neurotransmitters.

This review aims to explore the different approaches to evaluate the psychobiotic potential of several bacterial strains and fermented products.

The reviewed literature suggests that the consumption of psychobiotics could be considered as a viable option to both look after and restore mental health, without undesired secondary effects, and presenting a lower risk of allergies and less dependence compared to psychotropic drugs.”

— Excerpts from “Psychobiotics: Mechanisms of Action, Evaluation Methods and Effectiveness in Applications with Food Products,” Nutrients, 2020

From Microbiome Labs

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BiomeFx™ Stool Kit Test and Consultation Package

Janet Zarowitz, MS, RD, CDN — Tue, 22 Jul 2025 14:20:08 +0000

BiomeFx Stool Kit Test and Consultation Package — Includes At-Home Test Kit, Report and Consultation on Your Gut Microbiome

Do you know the status of your gut microbiome? Why does the gut microbiome matter?

Can BiomeFxStool Kit report explain GI symptoms like bloating and IBS?

Your gut microbiome is key to your digestive health AND your overall health!

Get a personalized state of the art analysis of your gut microbiome and professional consultation.

BiomeFx Stool Kit from Microbiome Labs, provides insight into how to optimize your gut health, through targeted diet, probiotics, other supplements and lifestyle

Uses best available testing — Whole Genome Sequencing — market’s most accurate stool sampling test to assess your gut microbiome

99.9% Specificity and over 95.7% Sensitivity of gut microbiome

At home/mail-in test with consultation on your report

Cutting-edge reporting system with actionable insights into:

Critical keystone species – counts of 14 species
Potential pathogens – levels of 29 species
Microbiome functions – analysis of 14 functions
Essential vitamins – insights into 8 vitamins
Metabolites – over or underproduced metabolites

What the BiomeFxStool Kit Package Includes:

BiomeFx Stool Kit (one)
BiomeFxStool Kit Report (takes about two weeks once lab receives sample)
Telehealth Video Consultation with Janet Zarowitz, MS, RD, CDN to explain and interpret your results of BiomeFx Stool Kit test
Personalized Recommendations on what is found on the BiomeFx Stool Kit Report
Free Shipping (both to receive and to return completed sample)

BiomeFx Stool Kit Report Interpretation

View Sample BiomeFx Stool Kit Report

After the stool sample has been analyzed, we will email you your report and schedule a personalized video telehealth appointment with Janet Zarowitz, MS, RD, CDN to interpret your report and make personalized recommendations.

The consultation will include:

Identifying dysbiosis ratios
Pinpointing which metabolites are over or under produced, and
Recommendations to support specific gut functions and microbes through diet, probiotics, supplement protocols and lifestyle recommendations.

Instructions for Ordering BiomeFx Stool Test Kit from New York State

There are limitations to BiomeFx Stool Kit in New York State. The BiomeFx collection kit must be shipped to the patient to an address outside of New York State.

However, you can return ship the completed BiomeFxStool kit with sample from a New York State address.

When ordering on this website, please make sure your checkout cart has a shipping address within the US, but outside of New York State.

Why Can Your Gut Microbiome Reveal A Lot About Your Health?

Trillions of tiny microorganisms thrive in the gut microbiome, including bacteria, yeast, fungi, and more. This bustling ecosystem drives health, from immunity and digestion to mood, metabolism and beyond.

Every microbe in the gut community has a job. Some break down food and even produce nutrients like vitamin K2, vitamin B 12, folate and other B vitamins.

Some beneficial microbes produce metabolites (like short chain fatty acids) which help maintain a normal level of inflammation in the gut and nourish cells lining the lower GI tract.

Other microbes balance pH, maintain the gut lining and support immunity and a healthy histamine response.

Did you know that the gut microbiome even affects your emotional well-being through the gut-brain axis? The gut flora produce hormones and neurotransmitters and even recycle estrogen!!!

Every type of microbe has a role in the GI tract. That includes opportunistic microflora as long as they remain in check. However, when biodiversity weakens and optimal balance falters, the entire microbial community is affected, resulting in dysbiosis. The far-reaching effects of dysbiosis often manifest beyond the gut as seemingly unrelated, body-wide impacts.

The BiomeFx Stool Kit explores the pathogens in your gut as well as the keystone species that are crucial to overall health and the metabolic functions that rely on the gut microbiome.

The BiomeFx Stool Kit report will identify which critical keystone species need to be supported and which potential pathogens need to be rebalanced — through diet, lifestyle, probiotics and supplements.

Integrative Nutritionist Janet Zarowitz, MS, RD, CDN will discuss a plan with you, to help optimize your gut microbiome.

Did Know That Certain Microbes are Associated with Obesity or Elevated BMI?

Yes, certain microbes are associated with metabolism. The gut microbiomes of lean people differ from the gut microbiomes of obese body types. Microbes can affect insulin sensitivity and are thought to be key to the underlying development of Type 2 Diabetes!

Even thousands of years ago, Hippocrates (400 B.C.) was aware of the gut’s key importance to health. Since that time, modern science has supported that belief.

Today healthcare practitioners understand that immune dysfunction (auto-immune, allergies, food sensitivities, histamine intolerance, rashes, psoriasis, eczema, rheumatoid arthritis, gout, etc.) may be traced back to a dysfunction in the GI. So can inflammatory and metabolic conditions also be traced to underlying gut imbalances.

A healthy body starts with a healthy gut. It’s easy to think of the skin as the body’s barrier to the outside world, but so is the gut.

The gut allows us to interact with the environment (which includes food), taking in what is necessary and beneficial and keeping out (hopefully) what might be unnecessary or harmful.

Today the gut is referred to as the “second brain.” Modern science has shown us that mood, depression and other mental disorders are also connected to gut health. Some gut disorders like IBS are closely linked to anxiety.

As researchers try to uncover root causes of chronic diseases such as diabetes, heart disease, cancer, etc, they are also looking to the gut for answers.

Everything starts in the GI.

From Microbiome Labs.

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Ther-Biotic Saccharomyces boulardii, probiotic yeast formula

Janet Zarowitz, MS, RD, CDN — Wed, 10 Jan 2024 01:22:22 +0000

Ther-Biotic Saccharomyces boulardii

A Powerful, unique non-pathogenic yeast probiotic

Saccharomyces boulardii is a friendly probiotic yeast that augments the intestinal absorption of water and electrolytes during occasional diarrhea and increases stool concentrations of short-chain fatty acids that nourish GI mucosal cells.

Benefits and Features

Assists individuals with occasional diarrhea^†
Supports healthy inflammatory response, where inflammation is associated with occasional digestive discomfort^†
A beneficial yeast that stimulates the immune system and promotes digestive health^†
Naturally resistant to all antibacterial antibiotics; supports normal gastrointestinal microbiota during antibiotic use^†

Clinical studies show that Saccharomyces boulardii supports healthy intestinal function, promoting healthy bowel transit time.^†

Detail Overview

Saccharomyces boulardii is a non-pathogenic, transient yeast long used to support normal bowel transit time.^† It is a hardy, acid-resistant, temperature tolerant microorganism that is not affected by antibacterial agents. S. boulardii is genetically and functionally distinct from brewer’s yeast (S. cerevisiae) and different from pathogenic Candida species.

Saccharomyces boulardii increases the activities of intestinal brush border enzymes such as disaccharidases, a-glucosidases, alkaline phosphatases, and aminopeptidases.^†

Saccharomyces boulardii augments the intestinal absorption of D-glucose coupled with sodium that may enhance the uptake of water and electrolytes during occasional diarrhea.^† It increases stool concentrations of short-chain fatty acids that nourish colon mucosal cells.^† Saccharomyces boulardii modulates immunity by boosting intestinal secretion of IgA and increasing crypt cell immunoglobulin receptors.^† It supports a healthy inflammatory response, where inflammation is associated with occasional digestive discomfort.^†Research has found that Saccharomyces boulardii supports healthy intestinal function in an array of clinical settings, supporting healthy bowel transit time.

Note: Saccharomyces boulardii is completely unrelated to Candida albicans, C. tropicalas, C. krusie, and other Candida species that cause disease and overgrowth in the gastrointestinal and genitourinary tracts. (Candida species decrease the acidity of the gastrointestinal mucosal environment, ultimately making the intestinal mucosal membrane susceptible to invasion by potentially harmful bacteria and yeast.)

Saccharomyces boulardii exerts the opposite effect producing lactic and other acids known to inhibit undesirable yeast species. Saccharomyces boulardii is non-pathogenic (non-disease-causing) and has been shown in numerous clinical trials to be safe and effective.

Made by SFI Labs (new label of Klaire Labs)

^†^{These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat or prevent any disease.}

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MegaSporeBiotic For KIDS: Spore-Based Probiotic Gummies

Janet Zarowitz, MS, RD, CDN — Tue, 22 Aug 2023 15:56:57 +0000

MegaSporeBiotic For KIDS – Spore Based Probiotic Gummies

Supports Healthy Gut Microbiome, Gut Health, Immune Function

Delicious Berry Flavor, Formulated Especially for Children

No Artificial: Colors, Flavors, Sweeteners or Preservatives

MegaSporeBiotic Gummies for Kids are a 100% spore-based proprietary probiotic blend that supports a healthy gut microbiome by promoting microbial diversity, maintaining a healthy gut barrier, and supporting the immune system’s protective responses.

These delicious, easy-to-digest chewable gummies contain four strains of the beneficial, spore-forming Bacillus bacteria found in Microbiome Labs’ flagship spore-based probiotic supplement, MegaSporeBiotic.

Bacillus spores are robust probiotic bacteria that can survive digestion.

Foundational Gut Nutrition

Our ancestors had a diet brimming with nutrients and beneficial species of live bacteria because they lived off the land. These species of live bacteria evolved into an essential component of our digestive system known as probiotics. Probiotics regulate the digestive system, improve immune function and serve as the first line of defense against infections.

MegaSporeBiotic for Kids is a proprietary probiotic blend of 4 clinically studied pharmaceutical grade probiotic bacillus strains that also occur naturally in our environment.

Unlike most other probiotics, bacillus probiotic spores in MegaSporeBiotic for Kids thrive  in the gut and survive the acid in our stomachs when taken orally. When they arrive lower down in the gut, they are able to do their job.

One of the most profound effects of these bacillus probiotics is their ability to “police” the GI, reduce inflammation of the gut lining, aid digestion and modulate the immune system.

MegaSporeBiotic for Kids helps facilitate and support the growth of the “good guys” that are under-populated and can reduce the numbers of the bacterium that are overgrown. It creates a modulating effect on the microbiota, which has many health benefits.

Scientists are learning more and more about the importance of a healthy and balanced gut microbiome. For example, the gut bacteria actually send signals to our immune system, acting as the “General” of the immune system that protects you from infection.

Health in general starts in the gut.

Hippocrates said it in 400 B.C. and since then modern science has proven it. Any immune dysfunction (auto-immune, allergies, food sensitivities, rashes, psoriasis, eczema, rheumatoid arthritis, gout, etc.) can be traced back to a dysfunction in the GI. Any inflammatory condition can as well.

Why is a good probiotic so important for kids?

A healthy body starts with a healthy gut.

Establishing a healthy gut microbiome early in life is foundational to setting the stage for good health throughout life. The health of the immune system is directly related to the health of the gut.

The gut allows us to interact with the environment (which includes food), taking in what is necessary and beneficial and keeping out (hopefully) what might be unnecessary or harmful.

Now, modern science has shown us that weight control, mood, depression and other mental disorders are also connected to the gut (the second brain). Even chronic diseases such as diabetes, heart disease, cancer, etc. can be traced back to the gut.

Everything starts in the GI. It’s important to support the gut microbiome early in life.

Made by Microbiome Labs.

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Histamine Digest – PureMAX with DAOgest™

Janet Zarowitz, MS, RD, CDN — Mon, 21 Aug 2023 18:22:25 +0000

Histamine Digest PureMAX with DAOgest– For Those with Multiple Sensitivities and Higher DAO Needs

DAO – Diamine Oxidase Enzyme – Enzyme for Histamine Imbalance (Histamine Neutralizing Enzyme)

Purest Formulation of DAO from OmneDiem

4.8 mg of natural diamine oxidase per capsule delivering 40,000 HDU

Supports Healthy Degradation of Food-Derived Histamine

Many foods contain histamine and/or cause the release of histamine in the gut. Diamine Oxidase (DAO) is the primary enzyme responsible for degrading dietary histamine in the GI tract.

Some people don’t produce a sufficient amount of Diamine Oxidase (DAO).

In that case, providing an outside source of DAO such as the nutrition supplement Histamine Digest PureMAX may provide relief of symptoms from excessive histamine levels.

Histamine Digest PureMAX contains a patented form of DAO that releases the enzyme in the small intestine where it acts directly on dietary histamine.

(According to the International Society of DAO Deficiency, the main cause of the enzymatic dysfunction is a person’s genetics.)

How is OmneDiem Histamine Relief PureMAX Different From Omne Diem Histamine Digest?

Histamine Relief PureMAX contains 40,000 HDU of diamine oxidase per capsule vs Histamine Digest which contains 20,000 HDU diamine oxidase per capsule.

Histamine Relief PureMAX does not contain Vitamin C (ascorbyl palmitate) or catalase, both of which are in the regular Histamine Digest DAO product. The omission of these extra ingredients makes Histamine Relief PureMAX the preferred form of DAO for sensitive individuals.

Both Histamine Relief PureMAX and Histamine Digest have designed release capsules that ensure delivery to the small intestine.

Per the manufacturer OmneDiem, regarding their 2024 reformulation of Histamine Digest PureMAX:

“Diamine oxidase, like other enzymes, is a delicate molecule that is most active when it is kept away from extreme environments, heat and humidity being two examples. By keeping diamine oxidase’s specific needs in mind, we’ve been able to customize the manufacturing process keeping it more stable and more active during extraction to yield an increased enzymatic activity and more HDU. It is thanks to these improvements in manufacturing that we can obtain a higher enzymatic activity out of the same amount of starting material.”

What are some symptoms of histamine intolerance?

The ingestion of histamine-rich food or of alcohol or drugs that release histamine or block DAO may provoke diarrhea, headache, rhinoconjunctival symptoms, asthma, hypotension, arrhythmia, urticaria, pruritus, flushing, and other conditions in patients with histamine intolerance.
— From the American Journal of Clinical Nutrition

DAO Enzyme is Clinically Tested to Break Down Dietary Histamines

The DAO enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract.

DAO is not absorbed and does not have systemic activity. Click to see the biochemistry of how DAO helps break down histamine.

Is Histamine Intolerance the Same as Mast Cell Activation Syndrome (MCAS)?

Histamine Intolerance and Mast Cell Activation Syndrome are different, but related.

In Mast Cell Activation Syndrome, a condition when body’s innate immune system is hyperactive, mast cells release many different chemical mediators, with histamine being just one of them.

More Information – Great Resources About Histamine Intolerance

Histamine Intolerance & Mast Cell Activation Flow Chart – triggers and symptoms – from www.histamine-intolerance.info

International Society of DAO Deficiency – everything from what DAO deficiency is, its origins, foods high in histamines, foods which interfere with histamine metabolism (including DAO-blocking foods), latest international research

Swiss Interest Group Histamine Intolerance (SIGHI) – information about histamine related disorders (histaminosis) — including cooking tutorials, recipes, and links to apps for histamine food values.

Note: Histamine Digest PureMAX does not manage or address antibody-related or IgE-related food allergies.

From OmneDiem®

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MegaGuard – Nature’s Stomach Support

Janet Zarowitz, MS, RD, CDN — Mon, 10 Apr 2023 20:40:33 +0000

MegaGuard – Nature’s Stomach Support

Digestive Support
Balances H. Pylori
Supports Normal Digestion
Balances Stomach Acid

MegaGuard is a novel digestive aid that combines clinically-studied and highly concentrated licorice polyphenols, scientifically-validated extractions of artichoke, and high potency ginger to promote normal digestion, balance stomach acid and reduce occasional digestive discomforts such as gas, bloating and indigestion.

With the power of these herbs combined, MegaGuard provides unique and comprehensive digestive support, bowel regularity and gastric balance.

GutGard Licorice Flavonoids

Licorice (Glycyrrhiza glabra) has a long history of use for digestive support. In Ayurvedic and Traditional Chinese practice, licorice is well-known for its ability to support the gastric mucosa. One of the most commonly known compounds in licorice is a saponin called glycyrrhizin that has been used as an emulsifier and sweetener in the food industry. However, most supplements contain deglycyrrhizinated licorice (DGL) because large amounts of glycyrrhizin have been associated with serious adverse side effects like elevated blood pressure and lowered potassium levels.

Gutgard® licorice flavonoids are entirely different from DGL with respect to chemistry, composition, manufacturing, and mechanisms of action. While a classical extract of DGL does not contain any significant quantity of flavonoids, Gutgard® is standardized to contain more than 10% total flavonoids and less than 0.5% glycyrrhizin to avoid undesirable effects. More than 50 flavonoids have been identified in Gutgard® which have been shown to have beneficial activity for digestive support. Gutgard® licorice can also relieve occasional indigestion, bloating, and gas at 150mg/day.

Artichoke Leaf Extract

Artichoke (Cynara scolymus) leaf extract (ALE) has also been used traditionally as a digestive aid. The bitter compounds, particularly cynaropicrin, are responsible for the digestive benefits of artichoke.

ALE has been shown to support bile production, healthy liver function, and balanced blood lipids. In 2003, German researchers demonstrated that 640mg/day of artichoke leaf extract significantly improved digestive issues like occasional bloating and fullness. Though the study was conducted over 6 weeks, the majority of the study group saw results in the first week.

Ginger Root Extract (20% Gingerols)

Ginger (Zinziber officinalis) has been used as a digestive aid in Eastern practice for generations. Studies have demonstrated that ginger supports gastric emptying and can relieve occasional bouts of nausea and vomiting.

Gingerols and shogaols, the active polyphenolic compounds in ginger, appear to be responsible for such effects by weakly inhibiting cholinergic M3 and serotonergic 5-HT3 receptors.

Ginger extracts with a higher gingerol content (20-30% gingerols) are stronger and more effective at providing digestive support. In 2015, an Italian study of 126 patients found that the daily combination of 40 mg of ginger extracts (25-30% gingerols) with 200 mg of artichoke leaf extracts reduced the frequency of occasional digestive issues like nausea, bloating, early satiety, and abdominal discomfort 17% more effectively than just artichoke leaf extract alone.16

While most ginger extracts only contain 5% gingerols, MegaGuard contains 60 mg of potent ginger root extract (20% gingerols) for maximum strength.

From Microbiome Labs.

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MegaIgG2000 – Immunoglobulins POWDER

Janet Zarowitz, MS, RD, CDN — Mon, 10 Apr 2023 20:02:05 +0000

Mega IgG2000 – Dairy-free Immunoglobulins Powder

Immune Defense — Supports Mucosal Immunity
Neutralizes Environmental Toxins, Pathogen Associated Patterns (PAMPS) and Bacteria

Supports Healthy Detoxification

Significantly Reduces Inflammation and Intestinal Damage
Maintains Healthy Gut Mucosal Barrier Function
Clinically Studied to Support a Healthy Immune Response

Supports Healthy Digestion
Lactose-free, casein-free, and β-lactoglobulin-free

MegaIgG2000 is a dairy-free (bovine-based) immunoglobulin concentrate that supports healthy digestion and maintains healthy gut barrier function.

Unlike other immunoglobulins on the market (most of which are milk-derived), Mega IgG2000 is derived from bovine serum, making it lactose-free, casein-free, and β-lactoglobulin-free.

Supports Healthy Mucosal Immune System

This unique alternative to bovine colostrum supports a healthy mucosal immune system by decreasing immune activation and strengthening gut barrier function. The serum immunoglobulin in Mega IgG2000 has been the subject in over 10 published human clinical trials.

What is the Immune Response?

When an antigen enters the body, it elicits a response from the innate and adaptive branches of the immune system. The adaptive immune response utilizes B and T lymphocytes to find foreign antigens, neutralize them, and eliminate them from the body. B lymphocytes do this by producing antibodies, or immunoglobulins, that can bind to unwanted antigens and remove them from the system.

IgG, the Most Abundant Antibody

Immunoglobulin G (IgG) is the most abundant antibody in the system. It can be found in blood and extracellular fluid, allowing it to control infections in the body.

Immunoglobulins are proteins that function as antibodies to bind environmental toxins in the gut.

IgG antibodies can bind a variety of pathogens, including bacteria, viruses, and fungi, as well as their toxic by-products. Binding these toxins will neutralize them and allow the immune system to safely remove them from the body.

These IgG antibodies can reduce the damage of metabolic endotoxemia and neutralize LPS (lipopolysaccharides), an endotoxin that riggers mucosal activation.

MegaIgG2000 Neutralizes Many Bacterial Antigens

MegaIgG2000 Can be Used in Total Gut Restoration Program

Schedule an Integrative and Functional Nutrition Consultation to help your implement a program to restore your gut health.

From Microbiome Labs.

More About the Mucosal System
The mucosal system is a very important part of the human immune system. It is the main interface between the human body and the outside world.

The mucosal system contains 150 times more surface area than skin, which makes it one of the most important immune barriers.

The health of the mucosa determines how the body interacts with antigens; therefore the integrity of the intestinal mucosa can dictate overall immune function.

Mucosa are membranes that line various cavities in the body; some secrete mucus, a thick protective fluid.

The mucosal membrane in the gut functions to stop pathogens and other unwanted molecules from getting into the blood stream.

Health in general starts in the gut.
Hippocrates said it in 400 B.C. and since then modern science has proven it. Any immune dysfunction (auto-immune, allergies, food sensitivities, rashes, psoriasis, eczema, rheumatoid arthritis, gout, etc.) can be traced back to a dysfunction in the GI. Any inflammatory condition can as well.

A healthy body starts with a healthy gut, and too many people are unhealthy because of an unhealthy gut. It’s easy to think of the skin as the body’s barrier to the outside world, but so is the gut.

The gut allows us to interact with the environment (which includes food), taking in what is necessary and beneficial and keeping out (hopefully) what might be unnecessary or harmful.

Now, modern science has shown us that weight control, mood, depression and other mental disorders are also connected to the gut (the second brain). Even chronic diseases such as diabetes, heart disease, cancer, etc. can be traced back to the gut.

Everything starts in the GI.

The post MegaIgG2000 – Immunoglobulins POWDER appeared first on The Nutrition Supplement Dietitian.

MegaMucosa CAPSULES

Janet Zarowitz, MS, RD, CDN — Tue, 21 Feb 2023 22:53:01 +0000

Clinically Tested to Help Rebuild Healthy Mucosal Barrier

Foundational Gut Nutrition

Supports Healthy Immune Response in Gut Mucosa, Supports Microbial Diversity, Leaky Gut

First Complete Mucosal Support Supplement of its Kind, Formulated with Key Amino Acids, to Support a Healthy Mucosal Barrier.

Dairy-Free Immunoglobulins, Gut-healing Amino Acids and Citrus Polyphenols

Capsule Formulation

Works with MegaSporeBiotic Probiotic

Core Component of Total Gut Restoration program — Formulated to Rebuild a healthy mucosal barrier.

MegaMucosa Has 3 Main Components

#1 Dairy-Free Immunoglobulins
MegaMucosa contains dairy-free immunoglobulins clinically shown to support a healthy immune response in the mucosa and a state-of-the-art flavobiotic clinically shown to support microbial diversity and alleviate barrier dysfunction, otherwise known as leaky gut.

The dairy-free immunoglobulin concentrate supports healthy digestion, neutralizes environmental toxins, and helps to Rebuild protective intestinal barriers. These IgG antibodies can reduce the damage of metabolic endotoxemia and neutralize LPS (lipopolysaccharides), an endotoxin that riggers mucosal activation.

#2 Key Gut-Healing Amino Acids
MegaMucosa also contains four key amino acids that play an important role in the production of intestinal mucosa: L-proline, L-serine, L-cysteine and L-threonine. These four amino acids have been shown to increase Mucin2 production and stimulate mucin synthesis in the colon, resulting in a thicker and healthier mucosal barrier.

#3 Citrus Polyphenols
MegaMucosa contains a natural citrus extract (MicrobiomeX) rich in polyphenols that supports digestive health and immunity by increasing microbial diversity in the gut and improving gut barrier function.

A clinical study using 500 mg of citrus fruit extract found a significant increase in short-chain fatty acid (SFCA) composition and a reduction in fecal calprotectin. Both results suggest that citrus polyphenols can reduce inflammation and modulate the microbial composition in the gut.

MegaMucosa is a Core Component of the 3- Pronged Total Gut Restoration Program from Microbiome Labs

The 3-pronged program is based on:
1. Reconditioning the gut with MegaSporeBiotic 100% bacillus probiotic to increase microbial diversity and encourage growth of key health-promoting, commensal gut bacteria (even during antibiotic therapy).

2. Reinforcing the beneficial microbial changes created by MegaSporeBiotic with MegaPreBiotic to promote a strong and diverse microbiome. It is composed of clinically-tested non-digestible oligosaccharides that can increase microbial diversity and selectively feed beneficial bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria.

3. Rebuilding the intestinal mucosa/addressing leaky gut with MegaMucosa, containing key amino acids, dairy-free immunoglobulins and citrus-based flavobiotic.

See the Total Gut Restoration Program Chart!

You can schedule an Integrative and Functional Nutrition Consultation to help your implement your Total Gut Restoration program.

More About the Mucosal System

The mucosal system is a very important part of the human immune system. It is the main interface between the human body and the outside world. The mucosal system contains 150 times more surface area than skin, which makes it one of the most important immune barriers.

The health of the mucosa determines how the body interacts with antigens; therefore the integrity of the intestinal mucosa can dictate overall immune function.

Mucosa are membranes that line various cavities in the body; some secrete mucus, a thick protective fluid.

The mucosal membrane in the gut functions to stop pathogens and other unwanted molecules from getting into the blood stream.

Health in general starts in the gut.
Hippocrates said it in 400 B.C. and since then modern science has proven it. Any immune dysfunction (auto-immune, allergies, food sensitivities, rashes, psoriasis, eczema, rheumatoid arthritis, gout, etc.) can be traced back to a dysfunction in the GI. Any inflammatory condition can as well.

A healthy body starts with a healthy gut, and too many people are unhealthy because of an unhealthy gut. It’s easy to think of the skin as the body’s barrier to the outside world, but so is the gut.

The gut allows us to interact with the environment (which includes food), taking in what is necessary and beneficial and keeping out (hopefully) what might be unnecessary or harmful.

Now, modern science has shown us that weight control, mood, depression and other mental disorders are also connected to the gut (the second brain). Even chronic diseases such as diabetes, heart disease, cancer, etc. can be traced back to the gut.

Everything starts in the GI.

From Microbiome Labs

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HU58 – High Potency Bacillus subtilis Probiotic

fulfilled_adnxrd — Thu, 19 Aug 2021 12:27:08 +0000

Bacillus Subtilis – High Potency Probiotic, Natural Antibiotic Producer

Produces Targeted Antibiotics in Intestines
Effective During Antibiotic Therapy

Formulated to Enhance Efficiency of MegaSporeBiotic

40% Increase in Short-Chain Fatty Acid (SCFA) Production

When additional gut microbiome support is needed, HU58 can be taken with (or without) MegaSporeBiotic to support:

healthy gut flora balance
healthy digestion
healthy immune function
healthy gut response in conditions with intestinal inflammation

Survivability in the Gut

Bacillus subtilis in HU58 is a very robust probiotic that forms an outer protective shell, known as an endospore. This impenetrable coating protects the bacterium from harsh environments, including heat, acid, pressure, light, and lack of oxygen. The rugged nature of Bacillus subtilis makes it the perfect probiotic to survive manufacturing, packaging, shipping, and ultimately digestion. In fact, this species is so resilient that researchers at California Polytechnic State University reported reviving Bacillus spores from the gut of a 25-million-year-old bee that was fossilized in amber.

The HU58 strain of Bacillus subtilis is a friendly bacterial spore that was discovered in a healthy human gut at the University of London. HU58 is an incredibly rugged spore that can withstand extreme pH levels, high temperatures, dehydration, antibiotics, pressure, radiation and even the harsh environment of the digestive tract. It can also produce over 12 targeted antibiotics of its own, which makes it particularly effective at balancing gut flora.

Supports Healthy Digestion
You may have heard that “you are what you eat,” but a more accurate phrase would be that “you are what you digest and absorb.” Digestion begins in the mouth with digestive enzymes present in saliva. Your body then relies on you to chew your food into small pieces before sending it through your stomach acid for further breakdown. Once your food passes through the stomach, the final step of digestion relies almost entirely upon the digestive enzymes from your pancreas.

Bacillus subtilis (HU58) is able to produce nearly 12 strong antibiotics that are potent fighters of opportunistic and harmful bacteria.

Bacillus subtilis (HU58) helps to maintain healthy digestion by increasing the production of digestive enzymes in the gut, including amylase, protease, and lipase.
Bacillus subtilis (HU58) produces a very healthy compound called Nattokinase; Nattokinase has been shown to reduce blood pressure, reduce cholesterol and reduce excessive clotting by fibrinolysis.
Bacillus subtilis (HU58) produces nutrients that have systemic health benefits such as B vitamins and Vitamin K2.
Bacillus subtilis (HU58) offers the effect of broad-spectrum immune stimulation.

Unlike most other probiotics, bacillus probiotic spores thrive  in the gut and survive the acid in our stomachs when taken orally. When they arrive lower down in the gut, they are able to do their job.

You can schedule an Integrative and Functional Nutrition Consultation for a personalized gut restoration plan.

Made by Microbiome Labs.

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GI Guard – Gastric Comfort, Health

fulfilled_adnxrd — Thu, 19 Aug 2021 12:25:04 +0000

GI Guard

With PepZin GI (zinc-carnosine), Mastic Gum and Slippery Elm botanicals
Nutrition for Gastric Health Support, Comfort

GI Guard is a formulation for GI health combining the clinically studied ingredient, PepZin GI® with time-tested mastic gum and slippery elm botanicals as well as the antacid calcium carbonate.

A Healthy Mucosal Lining is Foundational

GI Guard is designed to help support the integrity of the lining of the GI tract and provide gastric comfort.

The stomach’s protective mucin barrier must be intact in order to protect the stomach. The epithelial cells lining the GI tract have a very rapid turnover rate and require a continuous supply of nutrients for regeneration.

About PepZin GI (zinc-carnosine)

Clinical studies have demonstrated that PepZin GI can help to support GI health and promote gastric comfort such as occasional heartburn, nausea, bloating and upset stomach. Pepzin GI has been used in Japan since the 1990’s to support GI health.

PepZin GI promotes normal mucous secretion, combats free radicals, and supports stable cell membranes. Its cytoprotective and tissue repairing actions in the gut have been clinically studied.

PepZin GI® helps to maintain the integrity of the stomach lining and its proper immune responses to the typically harsh gastric environment.

In addition, PepZin GI supports a healthy gastric microbial balance and the lining throughout the GI tract.

Zinc-carnosine supports the natural protective mechanisms in the GI tract without suppressing stomach acid production or neutralizing it, or otherwise interfering in the normal digestive process.

Did you know that the much maligned stomach acid is necessary for proper protein digestion, mineral absorption and vitamin absorption, and to kill pathogens?

Clinical studies demonstrate endoscopically that PepZin GI can help to support GI health, with demonstrable effects within 4-8 weeks.

For more information on PepZin GI:

About Mastic Gum

Mastic, the resin of Pistacia lentiscus, a shrub of the sumac family (Anacardiaceae) has been used as a medicine since antiquity. It continues to be used in traditional folk medicine. In fact, Hippocrates wrote that the mastic is good for prevention of digestive problems and colds!

Today mastic is used for gastric and duodenal ulcers, respiratory conditions, muscle aches, and to improve circulation. Also, it is used for bacterial and fungal infections and may help decrease inflammation in the intestinal tract.

According to the Natural Medicines database, “Clinical research suggests that taking mastic gum 350 mg orally three times daily for 3 weeks improves symptoms, including general stomach pain, stomach pain when anxious, heartburn, and upper abdominal pain, in a greater percentage of patients with functional dyspepsia compared with placebo.”

Mastic gum has also been found to be helpful with symptoms and healing of gastric ulcers.

Because of its gummy consistency, mastic gum is used in some food products like chewing gum, ice creams, sauces, jams, desserts, puddings and cakes.

About Slippery Elm

The inner bark of the slippery elm tree is well known for its help in soothing sore throats (it’s used in throat lozenges). But it can also stimulate protective mucous secretion to support stomach and intestinal health!

Slippery elm is used traditionally to treat inflammation of the digestive system.

About Calcium Carbonate

Calcium carbonate works by binding to and neutralizing excess acid produced by the stomach. It provides instant, quick relief of the pain and discomfort of indigestion, heartburn and other symptoms that may be related to excess stomach acid.

GI Guard can be taken in the morning and evening. When taken in the evening it is often paired with a melatonin supplement.

PepZin GI® is a registered trademark of Hamari Chemicals, Ltd.

GI Guard is from Protocol for Life Balance.

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