Product Description
P-5-P Activated Vitamin B6
Targeted Support for SNPs in the Methylation Pathway
Pyridoxal-5-phosphate
Part of PureGenomics Program – Based on Nutrigenomics
This supplement provides 50 mg. of activated B6 (pyridoxal-5-phosphate), the predominant form of circulating B6.
People with genetic variations in the CBS gene may have an up-regulation in this gene. Thus they may have an increased requirement for P-5-P.
Why P-5-P, the Activated Vitamin B6 Preferred?
An “Insurance Policy”
P-5-P is the special form of Vitamin B6 that your body can easily utilize. It’s the activated form of B6. In fact, the other forms of B6 have to first be converted into P-5-P in order for their bodies to be able to use it.
The forms of Vitamin B6 that have to be converted into P-5-P in order to be utilized as a coenzyme are: pyridoxine, pyridoxal, or pyridoxamine.
Conversion of non-P-5-P forms of Vitamin B6 to P-5-P occurs in the intestinal absorptive cells or the liver.
But what if this conversion is not optimal? This can be the case in older adults, people with impaired liver function or those with GI issues, (e.g. celiac disease or GI inflammation).
I view taking Vitamin B6 in its active form (P-5-P) as an “insurance policy,” especially if a person has an increased requirement for it. (People with a CBS SNP may have an increased requirement for Vitamin B6.) Following absorption, the body is able to utilize the benefits of this very important vitamin.
Physiological Roles of Vitamin B6
Vitamin B6 plays many key roles in the body. For example Vitamin B6 is needed for:
- amino acid metabolism and neurotransmitter production and detoxification
- proper absorption of vitamin B12 and magnesium
- production of gastric acid needed for digestion and gut microbial health
- production of antibodies and red blood cells
- energy production in the liver and muscles
- metabolism of carbohydrates and fats
- maintaining sodium and potassium balance (Na:K balance regulates body fluids and promotes the healthy functioning of the nervous and musculoskeletal systems.)
- reducing pain and inflammation in early stages of carpal tunnel syndrome
Manufactured and formulated by Pure Encapsulations, Sudbury, MA.
The PureGenomics™ Program
This unique platform utilizes genetic information from the 23andme affordable at home test to help more effectively treat patients and their individual needs.
The protocol targets eight key Single Nucleotide Polymorphisms (SNPs) in the methylation pathway (one of which is COMT) that can be supported with nutrition.
Contact me if you are interested in learning more about, or participating in PureGenomics, the nutrigenomics program, from Pure Encapsulations.
