Product Description
(PEA)+ Palmitoylethanolamide with Meriva Curcumin
For Relief of Physiological Stress Soreness or Discomfort Associated with Occasional Pain, Stiffness and Compromised Tissue Function as a Result of Overexertion and Everyday Stress
PEA (Palmitoylethanolamide) is an extensively researched natural ingredient for important neuroprotective actions. In combination with the Meriva (curcumin), the (PEA)+ formula provides natural pain and anti-inflammatory support for the entire body with a focus on the body’s nervous, immune, and muscular systems.
The body makes its own PEA. In optimal health, the body’s natural production of PEA is in homeostasis. This balance can sometimes be compromised due to negative stimuli. As a result, the response to this threat of imbalance can cause a deficiency in PEA production. Supplementation of (PEA)+ works with the body to support this delicate balance, calm discomfort, and promote levels for wellbeing.
PEA (Palmitoylethanolamide) and Chronic Pain
“A growing body of evidence suggests that neuroinflammation, which is characterized by infiltration of immune cells, activation of mast cells and glial cells, and production of inflammatory mediators in the peripheral and central nervous systems, has an important role in the induction and maintenance of chronic pain.
These findings support the notion that new therapeutic opportunities for chronic pain might be based on anti-inflammatory and pro-resolving mediators that act on immune cells, in particular mast cells and glia, to mitigate or abolish neuroinflammation.
Among anti-inflammatory and pro-resolving lipid mediators, palmitoylethanolamide (PEA) has been reported to down-modulate mast cell activation and to control glial cell behaviors.” — Pain Physician, February 2016
PEA (Palmitoylethanolamide), Curcumin and Viruses
Researchers have found that patients with influenza and common cold who are treated with PEA have decreased symptoms, including acute respiratory disease. Scientists believe that this is due to PEA’s downregulation of a number of pro-inflammatory cytokines.
Based on the understanding of the working mechanisms of PEA, many integrative healthcare practitioners believe PEA may be helpful with severe cases of COVID-19 who develop a potentially fatal inflammatory cytokine storm.
Curcumin has also been shown to modulate the uncontrolled release of pro-inflammatory cytokines (activated by coronavirus) that can lead to the sometimes irreversible damage to the airway epithelium.
Over 80 Years of Research
PEA was identified over 80 years ago when it was isolated from animals. It was later found to be contained in chicken egg yolk, olive oil, safflower and soy lecithin, peanut meal, and several other foods.
In the 1990’s professor and Nobel laureate Rita Levi-Montalcini and her group identified the anti-inflammatory and analgesic properties and mechanism of action of PEA.
PEA is an endogenous fatty acid amide (FAA) that belongs to the family of biologically active lipids that are increased by the body to soothe discomfort naturally.
FAAs like PEA play a role in intracellular signaling to resolve factors that lead to cellular stress and inflammation. PEA is incorporated into cell membranes and works in concert with the endocannabinoid system.
Natural Form of PEA from Safflower Lecithin
There are two sources of PEA commercially available. Synthetic forms require the use of powerful synthetic solvents such as toluene. On the other hand, PEA can be naturally derived from safflower lecithin. (PEA)+ only utilizes naturally derived palmitoylethanolamide from safflower seed.
The health benefits have been demonstrated in hundreds of scientific investigations including over 20 double-blind human clinical trials.
Enzyme Science offers (PEA)+, a unique blend of PEA, from safflower seed, paired with the well-researched, patented, and highly bioavailable curcumin, Meriva” Phytosome.
If you are intrigued and want more technical information about PEA.
Manufactured by Enzyme Science.
