Product Description
Histamine Digest PureMAX with DAOgest™– For Those with Multiple Sensitivities and Higher DAO Needs
DAO – Diamine Oxidase Enzyme – Enzyme for Histamine Imbalance (Histamine Neutralizing Enzyme)
Purest Formulation of DAO from OmneDiem
4.8 mg of natural diamine oxidase per capsule delivering 40,000 HDU
Supports Healthy Degradation of Food-Derived Histamine
Many foods contain histamine and/or cause the release of histamine in the gut. Diamine Oxidase (DAO) is the primary enzyme responsible for degrading dietary histamine in the GI tract.
Some people don’t produce a sufficient amount of Diamine Oxidase (DAO).
In that case, providing an outside source of DAO such as the nutrition supplement Histamine Digest PureMAX may provide relief of symptoms from excessive histamine levels.
Histamine Digest PureMAX contains a patented form of DAO that releases the enzyme in the small intestine where it acts directly on dietary histamine.
(According to the International Society of DAO Deficiency, the main cause of the enzymatic dysfunction is a person’s genetics.)
How is OmneDiem Histamine Relief PureMAX Different From Omne Diem Histamine Digest?
Histamine Relief PureMAX contains 40,000 HDU of diamine oxidase per capsule vs Histamine Digest which contains 20,000 HDU diamine oxidase per capsule.
Histamine Relief PureMAX does not contain Vitamin C (ascorbyl palmitate) or catalase, both of which are in the regular Histamine Digest DAO product. The omission of these extra ingredients makes Histamine Relief PureMAX the preferred form of DAO for sensitive individuals.
Both Histamine Relief PureMAX and Histamine Digest have designed release capsules that ensure delivery to the small intestine.
Per the manufacturer OmneDiem, regarding their 2024 reformulation of Histamine Digest PureMAX:
“Diamine oxidase, like other enzymes, is a delicate molecule that is most active when it is kept away from extreme environments, heat and humidity being two examples. By keeping diamine oxidase’s specific needs in mind, we’ve been able to customize the manufacturing process keeping it more stable and more active during extraction to yield an increased enzymatic activity and more HDU. It is thanks to these improvements in manufacturing that we can obtain a higher enzymatic activity out of the same amount of starting material.”
What are some symptoms of histamine intolerance?
The ingestion of histamine-rich food or of alcohol or drugs that release histamine or block DAO may provoke diarrhea, headache, rhinoconjunctival symptoms, asthma, hypotension, arrhythmia, urticaria, pruritus, flushing, and other conditions in patients with histamine intolerance.
— From the American Journal of Clinical Nutrition
DAO Enzyme is Clinically Tested to Break Down Dietary Histamines
The DAO enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract.
DAO is not absorbed and does not have systemic activity. Click to see the biochemistry of how DAO helps break down histamine.
Is Histamine Intolerance the Same as Mast Cell Activation Syndrome (MCAS)?
Histamine Intolerance and Mast Cell Activation Syndrome are different, but related.
In Mast Cell Activation Syndrome, a condition when body’s innate immune system is hyperactive, mast cells release many different chemical mediators, with histamine being just one of them.
More Information – Great Resources About Histamine Intolerance
Histamine Intolerance & Mast Cell Activation Flow Chart – triggers and symptoms – from www.histamine-intolerance.info
International Society of DAO Deficiency – everything from what DAO deficiency is, its origins, foods high in histamines, foods which interfere with histamine metabolism (including DAO-blocking foods), latest international research
Swiss Interest Group Histamine Intolerance (SIGHI) – information about histamine related disorders (histaminosis) — including cooking tutorials, recipes, and links to apps for histamine food values.
Note: Histamine Digest PureMAX does not manage or address antibody-related or IgE-related food allergies.
From OmneDiem®
Histamine Digest PureMAX – Ingredients
