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Diabetes + the Microbiota

Diabetes + the Microbiota

Did you know that researchers believe that an imbalance of the gut microbiome is the underlying root cause for the onset of diabetes?

Here’s a simplified explanation of how diabetes can develop:

Chronic inflammation in the gut from microbial dysbiosis and lack of microbial diversity leads to damage to the gut mucosal barrier. Eventually this inflammation leads to gaps in the intestinal lining, known as leaky gut.

Through these gaps, toxins, pathogens and dietary antigens get through and trigger an inflammatory immune response.

Over time, this immune response may eventually cause insulin resistance and hyperglycemia and the eventual development of Type 2 diabetes.

Leaky gut also leaves those genetically predisposed to Type 1 diabetes with a poorly educated immune system, more vulnerable to viral triggers of the disease as well as damage to pancreatic beta cells.

A healthy gut microbiome is needed to tend the gut lining. We need our gut microbes to help us reduce intestinal inflammation and maintain the mucus barrier and tight junctions of the gut lining. The gut lining is a critical way that the body protects itself from the outside world.

I work with clients to rebalance their gut microbiota, through diet and supplements. My nutrition strategies are designed to increase microbial diversity as well as specifically increase populations of microbial species that will tend the gut lining.

These strategies support species of microbes that produce anti-inflammatory metabolites like butyrate and keep the gut mucus layer strong.

Here’s an illustration from Microbiome Labs comparing a healthy gut lining with a leaky gut lining.

Gut Dysbiosis, with decreased microbial diversity and a deficiency of butyrate producing and mucin supporting bacteria, can lead to leaky gut.
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