Skip to main content
Gut Health

Vitamin B12 Shapes Microbial Communities

By May 8, 2017January 23rd, 2024No Comments
B12 shapes microbial communities

Of course we are not microbes, but your intestinal tract is the host to about 100 TRILLION bacteria and other microbes, about three pounds worth.

These microbes make up a complex ecological system, that when in balance, provides us with protection from the “outside” elements.

So, when I read this article about how Vitamin B12 helps shape microbial communities, that only a few organisms can produce it but it’s needed by nearly all of them, I was intrigued.

“Vitamin B12 has an importance to microbial communities even greater than has been anticipated,” said chemist Aaron Wright of the Department of Energy’s Northwest National Laboratory.”

“Scientists have known that vitamin B12 controls crucial genes and enzymes in microbes involved in building DNA and proteins. But several scientists, including Andrew Goodman at Yale and Michiko Taga at University of California at Berkeley, have found indications that B12 wields even broader influence.”

“Wright’s team found that B12 interacts with 41 different proteins in the bacterium. They found that B12 is central to the regulation of folate, ubiquinone, and methionine—substances crucial to the ability of microbial cells to create energy, build proteins, repair DNA, and to grow….. The vitamin also changes the instructions it sends to genes depending on whether it’s day or night—not a surprise in a community of organisms for which light is a central driver.”

Read the research article.


Enough About Microbes, What About Vitamin B12 in Humans?

In humans Vitamin B12 is needed by every cell — B12 is needed to make DNA, the genetic material in each cell. It also helps keep nerve and blood cells healthy and is required for proper brain development and function. Studies like this provide new information about Vitamin B12 on a biochemical level.

Animal products are the best source of Vitamin B12, but in order to absorb it you need both adequate acid in the stomach and a protein your body makes, called the intrinsic factor.

A blood test is required to know if you have sufficient amounts of Vitamin B12. Make sure yours is up to date. Low levels can be boosted with a B12 nutrition supplement.